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Anti-Fibronectin antibody (ab2413) is a rabbit polyclonal antibody and is validated for use in ICC/IF, IHC-P, WB in human samples.

Anti-Fibronectin antibody (ab2413) has been cited over 977 times in peer reviewed journals and is trusted by the scientific community.

Abcam's high quality validation processes ensure Anti-Fibronectin antibody (ab2413) has high sensitivity and specificity.

Anti-Fibronectin antibody (ab2413) has 89 independent reviews from customers.

Anti-Fibronectin antibody (ab2413) specifically detects Fibronectin (UniProt ID: P02751; Molecular weight: 269kDa) and is sold in 250 µL selling sizes.

Fibronectin (FN1) is a glycoprotein that plays a critical role in the extracellular matrix (ECM) and is significantly upregulated in the tumor microenvironment. Fibronectin (FN1) facilitates tumor angiogenesis, providing essential nutrients to the growing tumor. It also aids in cancer cell invasion and metastasis through interactions with integrins and activation of signaling pathways like FAK/MAPK/ERK and Wnt. Additionally, fibronectin is involved in the epithelial-mesenchymal transition (EMT), which enhances the migratory and invasive capabilities of cancer cells.