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Anti-alpha smooth muscle Actin antibody [1A4] (ab7817) is a mouse monoclonal antibody and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-P and WB.

Anti-alpha smooth muscle Actin antibody [1A4] (ab7817) was first used in a scientific publication in 1986 and has been cited over 1242 times in peer reviewed journals. It's performance in Western blot, immunofluorescence and IHC in human, mouse and rat samples is trusted by the scientific community.

Abcam's high quality validation processes ensure Anti-alpha smooth muscle Actin antibody [1A4] (ab7817) has high sensitivity and specificity.

The specificity of Anti-alpha smooth muscle Actin antibody [1A4] (ab7817) has been confirmed by ICC/IF testing in alpha smooth muscle Actin knockout HeLa cells (ab264014).

Anti-alpha smooth muscle Actin antibody [1A4] (ab7817) has 103 independent reviews from customers.

Anti-alpha smooth muscle Actin antibody [1A4] (ab7817) specifically detects alpha smooth muscle Actin (UniProt ID: P62736; Molecular weight: 42kDa) and is sold in 100 ug and 1 mg selling sizes.

Conjugation-ready, carrier free format available for antibody clone 1A4 - ab240654.

Antibody clone 1A4 is also available pre-conjugated to a variety of labels for your convenience - Biotin, Alexa Fluor® 488, Alexa Fluor® 594, HRP, FITC (ab12557, ab184675, ab22368, ab23696, ab8211).

Alpha-Smooth Muscle Actin (α-SMA) is a critical protein involved in smooth muscle contraction, encoded by the ACTA2 gene. Predominantly found in vascular smooth muscle cells, α-SMA plays a vital role in fibrogenesis and wound healing. It is often used as a marker for myofibroblast formation, which are specialized cells that contribute to tissue repair and fibrosis. The expression of α-SMA is associated with the activation of myofibroblasts, making it an important indicator in studies of fibrosis and other related conditions.