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Anti-HSP60 Rabbit mAb

Heat shock protein 60 (Hsp60), also known as 60 kDa chaperonin (Cpn60), is a highly conserved protein that mainly exists in mitochondria and is very important for key protein folding introduced into mitochondria. When cells are damaged or stressed, HSP60 acts as a danger signal; and HSP60 can be used as an effective stimulator of immune response. HSP60 and its co-chaperone protein HSP10 can assist in the correct folding of nascent polypeptides, prevent misfolding and promote the refolding and correct assembly of unfolded polypeptides produced by the mitochondrial matrix under stress conditions. In addition, changes in the expression level of Hsp60 can be used as a marker for the prognosis or diagnosis of certain cancers and diseases.

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