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Anti-ATG7 Rabbit mAb

ATG7 is an E1-like ligase that plays a central role in autophagosome biogenesis by conjugating ATG5 to ATG12. It also participates in lipidation of the ATG8 family.74 The reduction in ATG7 protein level has been implicated as a causative factor in the Celiac disease (CeD) autoimmune and neurodegenerative diseases described below, by leading to reduced autophagic function.

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